strategy

An easy way to get the runner to flatline is to do 6 (3+3) damage on the corp's turn.
They have already lost their shields.

technique

money,money,money!! Meatdamage costs a fortune.

You have to look for combo parts, let her work a lot.

Unlucky! you drew the only disappointing card in the deck? let's deal with it Fast Advance.

Have you built up a sufficient account balance?
They already can't steal the agenda with enough bouncers.(It causes 6 damage)

Go about your business slowly, then shoot.

Lex Luthor

Skates shoes? Not scary at all, only during run can they avoid it.
Chip? ... That's right. Fortunately, though, very few players are using this chip.
If you think this deck recipe is a threat, how about one for your runner deck.

Anyway, Just rake in the money. Always be richer than opponent, don't rez ice Unnecessarily. There are only 7 agendas in this world. You will be fine.

What else you need

A mind that allows flatlined opponents (especially without knowing what happened by nurospike) to rudely exit the game.
(The rig they have worked so hard to set up suddenly comes to nothing, it is understandable.)